Monday 8 June 2020

Science and Engineering Problems Addressed by Advances in Optical Microscopy

New Illinois ECE research is advancing the field of optical microscopy, giving the field a critical new tool to solve challenging problems across many fields of science and engineering including semiconductor wafer inspection, nanoparticle sensing, material characterization, biosensing, virus counting, and microfluidic monitoring. The question is often asked, “Why can we not see or sense nanoscale objects under a light microscope?” The textbook answers are that their relative signals are weak, and their separation is smaller than Abbe’s resolution limit. 

However, the Illinois ECE research team, led by Illinois ECE Professor Lynford L Goddard, along with postdoc computer science vs computer engineering, and PhD student Aditi Udupa, is challenging these cornerstone principles with a brand-new optical framework. 


Their work, published in Nature Communications opens new doors to using optical microscopy to unravel difficult problems that impact our daily lives.  “Our work is significant not only because it advances scientific understanding of optical imaging but also because it enables researchers to directly visualize unlabeled objects that have deep sub-wavelength separations. We can see nanoscale structure without performing any image post-processing” said Goddard.

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